So a friend of mine gave his copy of the PC game Mass Effect 2. (He already bought the PC game when the Dragon Age 2 promo hit the Internet.) I immediately claimed the free Mass Effect 2 download from the Mass Effect 2 site. A night later, I ran into a Mass Effect 2 launch problem.
"Game cannot launch because of a misconfiguration. Please reinstall your game and try again," Windows complained. I groaned. I surfed for a solution and found several forums where people were complaining about their Dragon Age 2 freebie. I found the fix.
The solution after the jump.
[Note: Your problem might have a more simple solution. Please refer to my "EA Games Not Launching After Origin Update" article and check the solution there. If trying that doesn't crack it for you, navigate back here and try the fixes below.]
Your Mass Effect 2 launch problem, in all probability, might be the result of the following:
1. You have configured the EA Download Manager---Origin---(or Steam) to install games in a directory you have specified (not the default one).
In this case, go to the Mass Effect 2/Binaries folder and find a file labeled "EACore_App.ini." Open it with Notepad. See if the paths specified there follow the correct directory path that you have specified.
2. The game is being blocked by your Operating System's firewall.
In this case go once again to the Mass Effect 2/Binaries folder and find a file labeled "eacoreserver." Double click on that. A window should pop up asking you if would like to unblock or keep blocking the game. Click Unblock.
This should fix your Mass Effect 2 launch problems. If the above solutions do not work, please consult the Mass Effect 2 site forums.
Credit: I first read about this fix for the "Game cannot launch because of a misconfiguration. Please reinstall your game and try again" problem from DrPlote, a Mass Effect 2 site forum member.